Endocrine Abstracts

Introduction: Almost all type 1 diabetes mellitus (T1DM) patients have autoantibodies (ab) at disease onset. These ab prevalence varies according to patients’ age, origin and disease duration.Aim: Determine diabetes mellitus ab prevalence in a paediatric and adult T1DM Portuguese according to their age on diagnosis, gender and diabetes duration.Methods: Retrospective review of T1DM ab (glutamic acid decarboxylase 65 autoantibo...

Introduction: Hyperosmolar hyperglycaemic state (HHS) and diabetic ketoacidosis (DKA) are the two most serious acute metabolic complication of diabetes mellitus (DM). The authors propose to characterise the admissions for HHS and DKA at a univeristy hospital.Methods: An observational, descriptive, and retrospective study in adults admitted to the hospital between January 2009 and October 2013 due to HHS and DKA. The information was accessed via the patie...

The analogues of GLP-1(aGLP1) are a new class of anti-diabetic agents, administered subcutaneously for the treatment of Diabetes Mellitus type 2 (DM2). In the Portuguese market, there are two aGLP1 currently available: Liraglutide (once-daily administration) and Exenatide (once-weekly administration). They mimic the GLP-1, produced in the small intestine, stimulated by foods at this region, increasing the production of insulin, decreasing the satiety and slowing gastric emptyi...